Unravelling the Mystery Behind Mesothelioma Tumors
In what could be a step closer to a mesothelioma cure, French cancer researchers say they have identified two of the key genetic pathways responsible for triggering mesothelioma in asbestos-exposed people. Led by Inserm (The French National Institute of Health and Medical Research), the study focused on mice that had been genetically engineered with mutations on certain tumor-suppressor genes known to play a role in malignant mesothelioma in people. Learning About Human Mesothelioma from Mice In the experiment, published in the International Journal of Molecular Sciences, some of the genetically engineered mice, as well as some normal (wild type) mice, were exposed to asbestos while others were not. The goal was to understand exactly what is happening at the molecular…