Tag Archives: EPP

Still No Clear Answer on SMART Protocol for Pleural Mesothelioma

SMART protocol for mesothelioma

Another study is out and there is still no clear answer about the value of the SMART protocol for mesothelioma.  SMART stands for surgery for mesothelioma after radiotherapy. After studying nearly a hundred patients, doctors in Toronto say radical surgery after RT can be effective. But they also say it is still very hard to prevent serious complications, even in an experienced center like theirs.  The team at Princess Margaret Cancer Center tested the SMART protocol on previously-untreated pleural mesothelioma patients.  As with previous studies of the SMART protocol for mesothelioma, some of the patients did very well. Many lived longer than they would normally expect to live. But there was also a high incidence of serious surgery-related complications.  The … Continue reading Still No Clear Answer on SMART Protocol for Pleural Mesothelioma »

Age is a Factor in Mesothelioma Survival After Surgery

mesothelioma survival after surgery

Age appears to be one of the biggest predictors of mesothelioma survival after surgery. This holds true no matter which kind of surgery a patient has.  A new study from the University of Pennsylvania compared the outcomes of more than 2,000 mesothelioma surgery patients. They compared them by surgical type. They also compared their survival with that of people who did not have surgery. Mesothelioma survival after surgery was consistently longer for younger patients. The risk of death within a few months went up a little bit with each year of age. The news could help patients and doctors make better treatment decisions. Surgical Procedures for Mesothelioma Operating on mesothelioma patients is controversial. Mesothelioma tumors are irregularly shaped and difficult to … Continue reading Age is a Factor in Mesothelioma Survival After Surgery »

Lung-Sparing Surgery for Mesothelioma Superior to EPP, Study Says

Lung-Sparing Mesothelioma Surgery

A team of Japanese researchers have added their voices to the ongoing debate over lung-sparing surgery for mesothelioma. The researchers analyzed multiple studies on the different kinds of surgery for mesothelioma. The studies included more than 2,600 mesothelioma patients.  After a careful review of the data, the Japanese team concluded that lung-sparing surgery for mesothelioma is almost always better than removing a lung. Mesothelioma patients who had this type of surgery had much fewer complications. They lived just as long as those who had more radical mesothelioma surgery.  Radical and Conservative Mesothelioma Surgery Malignant mesothelioma is a membrane cancer caused by asbestos exposure. It usually occurs in the membrane around the lungs. About 20 percent of cases occur on the … Continue reading Lung-Sparing Surgery for Mesothelioma Superior to EPP, Study Says »

Black Mesothelioma Patients Less Likely to Receive Surgery

black mesothelioma patients

Black mesothelioma patients are less likely to receive potentially-life saving surgery than white patients, even though they have worse short-term mortality.   That is the finding of a new study published in the Journal of Immigrant and Minority Health.  Mount Sinai researchers used data from the National Cancer Institute to compare mesothelioma treatment trends among 2550 patients.  They concluded that both white and black mesothelioma patients live longer with surgery, but white patients tend to get the most benefit. Surgical Options for Malignant Mesothelioma Malignant mesothelioma is a membrane cancer. It can occur in different places in the body. The type of treatment varies depending on where the cancer occurs. For mesothelioma in the abdomen (peritoneal mesothelioma), surgery with a rinse … Continue reading Black Mesothelioma Patients Less Likely to Receive Surgery »

Researchers Argue Against Surgery for Mesothelioma

surgery for mesothelioma

A pair of California surgeons say surgery for mesothelioma is rarely worthwhile. They point to what they say are flawed studies on surgical treatment. One trial they believe was well-conducted seems to show reduced mesothelioma survival after surgery. Writing in the journal Translational Lung Cancer Research, the doctors argue that most patients should choose non-surgical treatment for mesothelioma.  Some Background on Surgery for Mesothelioma Pleural mesothelioma is a cancer of the lining around the lungs. It is an aggressive cancer with no known cure. There are two primary approaches to surgery for mesothelioma. Both types are controversial and the subject of much debate among surgeons.  Extrapleural pneumonectomy (EPP) is a surgical approach that involves removing the pleural membrane, one lung, … Continue reading Researchers Argue Against Surgery for Mesothelioma »

Surgery Extends Survival for Patients with Pleural Mesothelioma

patients with pleural mesothelioma

Patients with pleural mesothelioma who choose to have surgery live longer than those who do not. This applies no matter which kind of surgery they have.  That is the conclusion of a Mexican study published in the Annals of Oncology. Doctors with the country’s National Institute for Respiratory Diseases conducted the study. It included 122 pleural mesothelioma patients.  The researchers analyzed a wide range of variables like age, sex, asbestos exposure, and overall health. They discovered that the decision to have surgery was one of the most important survival factors in patients with pleural mesothelioma. Treatment Options for Patients with Pleural Mesothelioma Pleural mesothelioma is an aggressive cancer with no known cure. It usually occurs in people who have been … Continue reading Surgery Extends Survival for Patients with Pleural Mesothelioma »

Conservative Surgery Leads to Better Mesothelioma Survival After Recurrence

mesothelioma survival

Mesothelioma survival after recurrence may be better with lung-preserving P/D surgery than with more radical EPP. Japanese researchers recently analyzed the cases of 44 mesothelioma patients who underwent either EPP or P/D. It took about the same amount of time for mesothelioma tumors to start growing again, no matter what type of surgery the patient had. The difference was in survival. Both overall survival and mesothelioma survival after recurrence were longer in the P/D patients. EPP vs. P/D: The Ongoing Debate Mesothelioma surgeons around the world are still divided about which type of mesothelioma surgery is best. On one hand, extrapleural pneumonectomy (EPP) removes more diseased tissue, including a lung. Some say this improves the odds of long term mesothelioma … Continue reading Conservative Surgery Leads to Better Mesothelioma Survival After Recurrence »

Combination Therapy with Mesothelioma Surgery Leads to Longer Survival

Mesothelioma surgery patient with nurse

A new study finds almost a quarter of people who had combination therapy with mesothelioma surgery were still alive five years later. The study was published in the European Journal of Cardio-Thoracic Surgery. Researchers at University Hospitals KU Leuven in Belgium studied nearly 200 mesothelioma patients from 2003 to 2014. Many people do not live beyond about 18 months after a mesothelioma diagnosis. But the Belgian team says, for the right patients, there is a way to improve the odds. They say combination therapy with radical mesothelioma surgery offers a 1 in 4 chance of surviving for 5 years or more. Two Types of Mesothelioma Surgery There are two major schools of thought about mesothelioma surgery. Some surgeons say it … Continue reading Combination Therapy with Mesothelioma Surgery Leads to Longer Survival »

Survival After Mesothelioma Surgery Could Rise with Immunotherapy Spray

improving survival after mesothelioma surgery

A spray-on immune booster may one day improve survival after mesothelioma surgery. UCLA scientists tested the biodegradable spray gel in mice with advanced melanoma. They found that it stopped cancer recurrence after surgery in about half of the lab animals tested. “Around 90 percent of people with cancerous tumors end up dying because of tumor recurrence or metastasis,” says lead investigator Zhen Gu. “Being able to develop something that helps lower this risk for this to occur and has low toxicity is especially gratifying.” Gu is a professor of bioengineering and a member of the UCLA Jonsson Comprehensive Cancer Center where the spray was developed. Survival After Mesothelioma Surgery Survival after mesothelioma surgery or any other kind of cancer operation … Continue reading Survival After Mesothelioma Surgery Could Rise with Immunotherapy Spray »

Better Quality of Life from Lung-Sparing Mesothelioma Surgery

blowing

Mesothelioma patients who undergo pleurectomy/decortication (P/D) may enjoy a better quality of life afterward than those who have extrapleural pneumonectomy (EPP). That is the message of a new study published in the Asian Cardiovascular and Thoracic Annals. Pleural mesothelioma arises most often in the thin lining that surrounds the lungs. Because of its close proximity to the lungs, it is not uncommon for pleural mesothelioma to eventually spread to the lung itself, reducing its function. Eventually, the diseased mesothelium also thickens and stiffens, preventing the lungs from expanding adequately with each breath. Pleurectomy/decortication and extrapleural pneumonectomy are the two major types of surgical treatments for mesothelioma. There is great disagreement within the medical community as to which one is better for … Continue reading Better Quality of Life from Lung-Sparing Mesothelioma Surgery »