IMRT for Long-Term Survival After Mesothelioma Surgery
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IMRT for Long-Term Survival After Mesothelioma Surgery

ByAlex Strauss

Intensity modulated radiation therapy (IMRT) can safely slow or even stop mesothelioma progression after surgery as long as the dose is just right. A team of Texas radiation oncologists reached that conclusion after studying the treatment results of 18 mesothelioma patients between 2005 and 2014. IMRT is a highly targeted form of high-dose radiation. While it can have a powerfully negative effect on tumor cells, it can also have an equally negative effect on healthy lung tissue. Some patients have even died from pulmonary toxicity caused by IMRT. But in a report published in the journal Oncology, doctors from Texas A & M Medical Sciences Center and Baylor Scott and White Hospital found that, as long as the radiation dose…

Radiotherapy for Mesothelioma: Better But Still Limited
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Radiotherapy for Mesothelioma: Better But Still Limited

ByAlex Strauss

A form of highly-targeted radiation therapy for mesothelioma is better than it used to be, but is still risky. That is the message of a recent article on intensity-modulated radiation therapy (IMRT) in Seminars in Thoracic and Cardiovascular Surgery. Author Kenneth E. Rosenzweig, MD, a Radiation Oncologist with Mount Sinai Hospital in New York, reviewed recent studies on IMRT and mesothelioma. He concludes that, while the “troubling toxicity” associated with IMRT when it was first introduced has not been entirely eliminated, the fact that clinicians now have more experience with it is making a positive difference for mesothelioma patients. Before targeted therapies like IMRT were available, high-dose radiation was not usually a feasible option for mesothelioma since the irregular shape…

Radiotherapy for Mesothelioma: Experience Counts
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Radiotherapy for Mesothelioma: Experience Counts

ByAlex Strauss

When it comes to advanced radiotherapy techniques for mesothelioma, experience counts. That is the central message of a study conducted at Duke University Medical Center. Radiation Oncology researchers at Duke examined the records of mesothelioma patients who had received Intensity Modulated Radiation Therapy (IMRT) following surgery between 2005 and 2010.  All the mesothelioma patients had undergone extrapleural pneumonectomy (EPP), a radical procedure that involves the removal of the pleura and other membranes, a lung, and all or part of the diaphragm. Radiotherapy can be especially challenging for mesothelioma – a cancer of the membranes around organs – because so many critical structures are located so close to the treatment area.  IMRT is designed to help direct more radiation into tumors while…

IMRT Multimodality Therapy for Mesothelioma Appears Safe
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IMRT Multimodality Therapy for Mesothelioma Appears Safe

ByAlex Strauss

Pleural mesothelioma, a malignancy of the lung lining caused by breathing asbestos, is notoriously difficult to treat. While they can improve quality of life, traditional cancer therapies, including chemotherapy, radiation and surgical intervention have not been shown to improve survival rates in most mesothelioma patients beyond a few months. Researchers around the world are experimenting with advanced treatment options that may give mesothelioma patients new hope. A new study on Intensity Modulated Radiation Therapy (IMRT) as part of a multi-modality treatment protocol appears to show improved safety over earlier studies that incorporated the same technology. IMRT is an advanced method of radiotherapy that uses a linear accelerator to deliver precise high doses of radiation directly into a tumor. One of…