Tag Archives: pleural mesothelioma

Surgery for Mesothelioma: Goals and Side Effects

Surgery for Mesothelioma: Goals and Side Effects

Residual thoracic spaces occur in one-third of patients who receive surgery for mesothelioma. This is the space left after mesothelioma disease is removed from the lung. A new study by researchers in Japan details the results of an analysis of this side effect. Pleural Mesothelioma Mesothelioma is a rare form of cancer caused by exposure to asbestos. Treatment often combines surgery, chemotherapy, and radiation. Pleural mesothelioma is a type of cancer that develops from the thin layer of tissue that covers the lungs and chest wall. Symptoms may include shortness of breath due to fluid around the lung, chest pain, cough, and fatigue. This cancer is caused by exposure to asbestos. It can often take around 40 years for pleural … Continue reading Surgery for Mesothelioma: Goals and Side Effects »

A Multimodality Treatment Plan may be Best for Pleural Mesothelioma

A Multimodality Treatment Plan may be Best for Pleural Mesothelioma

A multimodality treatment plan may improve mesothelioma patient outcomes. Malignant pleural mesothelioma is an invasive, locally aggressive tumor related to asbestos exposure. A new study shows that the best treatment plan for pleural mesothelioma may be when different types of therapy work together. The ideal combination of treatment therapies is still unknown. But a recent study encourages further studies on a multimodality treatment plan. This may include chemotherapy, surgery, and adjuvant radiotherapy. Current Clinical Guidelines: A History of Single or Multimodality Treatment Plans Despite a long history of clinical research, there is still no cure or any evidence of the best treatment. Many single-treatment plans, single-modality plans, have had disappointing results. Researchers have begun to evaluate different multi-modal treatment approaches. … Continue reading A Multimodality Treatment Plan may be Best for Pleural Mesothelioma »

Lung-Sparing Surgery and Mesothelioma Survival

lung-sparing surgery

Italian researchers say lung-sparing surgery can lead to long-term mesothelioma survival, even if surgeons take a more conservative approach.  Lung-sparing surgery for mesothelioma is also known as pleurectomy with decortication (P/D). P/D surgery is less extensive than the other main surgical approach for mesothelioma but it is also less risky. Now, doctors at Venice-Mestre Hospital say that, as long as it is performed early enough and combined with other treatments, lung-sparing surgery saves lives. Their report in the Journal of Thoracic Disease details the outcomes of 155 mesothelioma surgery patients tracked for a median of a year-and-a-half.  Extrapleural Pneumonectomy & Lung-Sparing Surgery Extrapleural pneumonectomy (EPP) is the most radical operation for pleural mesothelioma. In addition to removing the mesothelioma tumor … Continue reading Lung-Sparing Surgery and Mesothelioma Survival »

Pleural Mesothelioma Risk Among Workers May Be Higher in Winter

pleural mesothelioma risk

A leading authority in the occupational health and safety space is warning workers to be aware that their pleural mesothelioma risk may be higher in the winter. The website Occupational Health & Safety says winter is a prime season for exposure to toxins like asbestos that can threaten respiratory health. Asbestos is the primary cause of malignant pleural mesothelioma worldwide. In a new online article, the site says the combination of dry air, colds and allergies, closed up work spaces, and poor ventilation can increase the risk for serious respiratory diseases.  Why Winter Can Be Dangerous for Workers Although anyone can get malignant mesothelioma, it is usually considered an occupational disease. People in certain kinds of jobs face a much … Continue reading Pleural Mesothelioma Risk Among Workers May Be Higher in Winter »

HITOC for Mesothelioma: Benefits May Outweigh the Risk

HITOC for mesothelioma

The benefits of a localized chemotherapy regimen known as HITOC for mesothelioma outweigh the small risk of kidney failure for most patients.  That is the conclusion of a new study published in the journal Cancers. German researchers conducted a retrospective review of the medical literature on HITOC (also called HITHOC) in pleural mesothelioma patients.  They were most interested in patients who developed kidney problems after the procedure. This is a known risk with HITOC for mesothelioma. But the study suggests that most patients benefit from this type of chemotherapy in spite of the risk. Localized Treatment Versus Systemic Treatment Pleural mesothelioma tumors start on the membrane around the lungs and are hard to treat. Once this cancer takes hold, most … Continue reading HITOC for Mesothelioma: Benefits May Outweigh the Risk »

HITHOC for Pleural Mesothelioma: “Safe, Feasible and Effective”

HITHOC for pleural mesothelioma

A newly published study says a localized form of chemotherapy called HITHOC for pleural mesothelioma is “safe, feasible, and effective.” Researchers from Italy’s University of Pisa conducted the study. They did a thorough review of the medical literature on the procedure since 1994.  They conclude that HITHOC for pleural mesothelioma after surgery keeps tumors in check and improves survival. The downside is that there is not enough standardization in how doctors use the procedure.  How HITHOC for Pleural Mesothelioma Works HITHOC stands for hyperthermic intrathoracic chemotherapy. Standard mesothelioma chemotherapy enters the whole body at once through the bloodstream. That is one reason that many mesothelioma patients on chemotherapy have side effects like nausea and low white blood cell counts.  HITHOC … Continue reading HITHOC for Pleural Mesothelioma: “Safe, Feasible and Effective” »

Neoadjuvant Chemotherapy Plus Surgery for Pleural Mesothelioma: A Prospective Study

neoadjuvant chemotherapy

A new prospective Japanese mesothelioma study shows the potentially life-saving benefits of undergoing neoadjuvant chemotherapy followed by surgery. This has been the preferred way to treat pleural mesothelioma for many years. But most of the studies on it are retrospective. This means that researchers analyze data on mesothelioma patients who already had treatment. In many cases, they are patients who have died.  The new study is one of the few prospective studies on neoadjuvant chemotherapy and mesothelioma surgery.  In a prospective study, researchers enroll patients and follow their progress through treatment.  Pleural mesothelioma is often fatal within a few months. But ninety-five percent of the study subjects who had presurgical chemotherapy followed by an operation were still alive a year … Continue reading Neoadjuvant Chemotherapy Plus Surgery for Pleural Mesothelioma: A Prospective Study »

New Study: Pure Talc is Not a Cause of Pleural Mesothelioma

cause of pleural mesothelimoa

New research out of Italy is further evidence that asbestos – and not other dusty minerals like talc – is almost always the cause of pleural mesothelioma. The evidence comes from a 50-year study of more than 1,700 Northern Italian talc miners and millers.  Talc and asbestos often lie close together in the ground. Some people who have worked in talc mines or even used talc products have developed malignant mesothelioma. Many of these mines and products were contaminated with asbestos. This makes it difficult to know if it was the talc or the asbestos that caused the cancer.  But the workers in the new study worked in a mine that was uncontaminated with asbestos. Analysis of their causes of death … Continue reading New Study: Pure Talc is Not a Cause of Pleural Mesothelioma »

LA Woman’s Story is a Sobering Reminder to Watch for Signs of Pleural Mesothelioma

signs of pleural mesothelioma

The plight of an LA actress who found out she had lung cancer because of a COVID test is a sobering reminder to be aware of the early signs of pleural mesothelioma. The woman’s story was recently featured on the Today Show website. Fifty-nine year old Annabelle Gurwitch is a non-smoker with no known lung cancer risk factors. She and her 23-year-old child decided to get COVID tests after her child came home from college.  Although the COVID test was negative, Gurwitch writes that doctors were concerned about her persistent cough. Ongoing cough can be a one of the early signs of pleural mesothelioma, too. An X-ray revealed that Gurwitch was suffering from Stage 4 lung cancer, the most common … Continue reading LA Woman’s Story is a Sobering Reminder to Watch for Signs of Pleural Mesothelioma »

Could Anti-Malaria Drug Become New Pleural Mesothelioma Treatment?

new pleural mesothelioma treatment

A new report  suggests an anti-malaria drug called quinacrine has potential as a new pleural mesothelioma treatment. Before chloroquine became more popular, quinacrine was widely used to treat malaria. Now doctors mostly use it for a diarrhea disease caused by a parasite. But a report published in the International Journal of Molecular Science says quinacrine also has anti-cancer properties. Laboratory tests suggest it has the makings of a powerful new pleural mesothelioma treatment. The Challenge of Pleural Mesothelioma Malignant mesothelioma starts on the membranes around internal organs. It can quickly spread to other parts of the body. Pleural mesothelioma grows on the lining around the lungs. It is almost always caused by exposure to asbestos dust.  Most people with mesothelioma … Continue reading Could Anti-Malaria Drug Become New Pleural Mesothelioma Treatment? »