Malignant Pleural Mesothelioma: Pleural Decortication and Multimodal Therapy
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A Multimodality Treatment Plan may be Best for Pleural Mesothelioma

ByHolly Zink

A multimodality treatment plan may improve mesothelioma patient outcomes. Malignant pleural mesothelioma is an invasive, locally aggressive tumor related to asbestos exposure. A new study shows that the best treatment plan for pleural mesothelioma may be when different types of therapy work together. The ideal combination of treatment therapies is still unknown. But a recent study encourages further studies on a multimodality treatment plan. This may include chemotherapy, surgery, and adjuvant radiotherapy. Current Clinical Guidelines: A History of Single or Multimodality Treatment Plans Despite a long history of clinical research, there is still no cure or any evidence of the best treatment. Many single-treatment plans, single-modality plans, have had disappointing results. Researchers have begun to evaluate different multi-modal treatment approaches….

Safer Surgery for Mesothelioma Patients: Promising Strategies Revealed in Recent Study

Lung-Sparing Surgery and Mesothelioma Survival

ByAlex Strauss

Italian researchers say lung-sparing surgery can lead to long-term mesothelioma survival, even if surgeons take a more conservative approach.  Lung-sparing surgery for mesothelioma is also known as pleurectomy with decortication (P/D). P/D surgery is less extensive than the other main surgical approach for mesothelioma but it is also less risky. Now, doctors at Venice-Mestre Hospital say that, as long as it is performed early enough and combined with other treatments, lung-sparing surgery saves lives. Their report in the Journal of Thoracic Disease details the outcomes of 155 mesothelioma surgery patients tracked for a median of a year-and-a-half.  Extrapleural Pneumonectomy & Lung-Sparing Surgery Extrapleural pneumonectomy (EPP) is the most radical operation for pleural mesothelioma. In addition to removing the mesothelioma tumor…

pleural mesothelioma risk
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Pleural Mesothelioma Risk Among Workers May Be Higher in Winter

ByAlex Strauss

A leading authority in the occupational health and safety space is warning workers to be aware that their pleural mesothelioma risk may be higher in the winter. The website Occupational Health & Safety says winter is a prime season for exposure to toxins like asbestos that can threaten respiratory health. Asbestos is the primary cause of malignant pleural mesothelioma worldwide. In a new online article, the site says the combination of dry air, colds and allergies, closed up work spaces, and poor ventilation can increase the risk for serious respiratory diseases.  Why Winter Can Be Dangerous for Workers Although anyone can get malignant mesothelioma, it is usually considered an occupational disease. People in certain kinds of jobs face a much…

Safety First: Managing Cisplatin Exposure After Mesothelioma Treatment
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HITOC for Mesothelioma: Benefits May Outweigh the Risk

ByAlex Strauss

The benefits of a localized chemotherapy regimen known as HITOC for mesothelioma outweigh the small risk of kidney failure for most patients.  That is the conclusion of a new study published in the journal Cancers. German researchers conducted a retrospective review of the medical literature on HITOC (also called HITHOC) in pleural mesothelioma patients.  They were most interested in patients who developed kidney problems after the procedure. This is a known risk with HITOC for mesothelioma. But the study suggests that most patients benefit from this type of chemotherapy in spite of the risk. Localized Treatment Versus Systemic Treatment Pleural mesothelioma tumors start on the membrane around the lungs and are hard to treat. Once this cancer takes hold, most…

Can TAMs Hold the Key to Stopping Cancer's Advances?
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HITHOC for Pleural Mesothelioma: “Safe, Feasible and Effective”

ByAlex Strauss

A newly published study says a localized form of chemotherapy called HITHOC for pleural mesothelioma is “safe, feasible, and effective.” Researchers from Italy’s University of Pisa conducted the study. They did a thorough review of the medical literature on the procedure since 1994.  They conclude that HITHOC for pleural mesothelioma after surgery keeps tumors in check and improves survival. The downside is that there is not enough standardization in how doctors use the procedure.  How HITHOC for Pleural Mesothelioma Works HITHOC stands for hyperthermic intrathoracic chemotherapy. Standard mesothelioma chemotherapy enters the whole body at once through the bloodstream. That is one reason that many mesothelioma patients on chemotherapy have side effects like nausea and low white blood cell counts.  HITHOC…

neoadjuvant chemotherapy
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Neoadjuvant Chemotherapy Plus Surgery for Pleural Mesothelioma: A Prospective Study

ByAlex Strauss

A new prospective Japanese mesothelioma study shows the potentially life-saving benefits of undergoing neoadjuvant chemotherapy followed by surgery. This has been the preferred way to treat pleural mesothelioma for many years. But most of the studies on it are retrospective. This means that researchers analyze data on mesothelioma patients who already had treatment. In many cases, they are patients who have died.  The new study is one of the few prospective studies on neoadjuvant chemotherapy and mesothelioma surgery.  In a prospective study, researchers enroll patients and follow their progress through treatment.  Pleural mesothelioma is often fatal within a few months. But ninety-five percent of the study subjects who had presurgical chemotherapy followed by an operation were still alive a year…

cause of pleural mesothelimoa
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New Study: Pure Talc is Not a Cause of Pleural Mesothelioma

ByAlex Strauss

New research out of Italy is further evidence that asbestos – and not other dusty minerals like talc – is almost always the cause of pleural mesothelioma. The evidence comes from a 50-year study of more than 1,700 Northern Italian talc miners and millers.  Talc and asbestos often lie close together in the ground. Some people who have worked in talc mines or even used talc products have developed malignant mesothelioma. Many of these mines and products were contaminated with asbestos. This makes it difficult to know if it was the talc or the asbestos that caused the cancer.  But the workers in the new study worked in a mine that was uncontaminated with asbestos. Analysis of their causes of death…

signs of pleural mesothelioma
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LA Woman’s Story is a Sobering Reminder to Watch for Signs of Pleural Mesothelioma

ByAlex Strauss

The plight of an LA actress who found out she had lung cancer because of a COVID test is a sobering reminder to be aware of the early signs of pleural mesothelioma. The woman’s story was recently featured on the Today Show website. Fifty-nine year old Annabelle Gurwitch is a non-smoker with no known lung cancer risk factors. She and her 23-year-old child decided to get COVID tests after her child came home from college.  Although the COVID test was negative, Gurwitch writes that doctors were concerned about her persistent cough. Ongoing cough can be a one of the early signs of pleural mesothelioma, too. An X-ray revealed that Gurwitch was suffering from Stage 4 lung cancer, the most common…

new pleural mesothelioma treatment
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Could Anti-Malaria Drug Become New Pleural Mesothelioma Treatment?

ByAlex Strauss

A new report  suggests an anti-malaria drug called quinacrine has potential as a new pleural mesothelioma treatment. Before chloroquine became more popular, quinacrine was widely used to treat malaria. Now doctors mostly use it for a diarrhea disease caused by a parasite. But a report published in the International Journal of Molecular Science says quinacrine also has anti-cancer properties. Laboratory tests suggest it has the makings of a powerful new pleural mesothelioma treatment. The Challenge of Pleural Mesothelioma Malignant mesothelioma starts on the membranes around internal organs. It can quickly spread to other parts of the body. Pleural mesothelioma grows on the lining around the lungs. It is almost always caused by exposure to asbestos dust.  Most people with mesothelioma…

Leveraging the Pleural Space for Anticancer Therapies in Pleural Mesothelioma
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Pleural Mesothelioma Rates Expected to Decline Just as Lung Cancer Deaths Have

ByAlex Strauss

A new report suggests that pleural mesothelioma rates will continue to decline worldwide over the next decade as many countries get wise to the dangers of asbestos. The report comes on the heels of another study showing dramatic declines in US lung cancer deaths.  The report on mesothelioma rates comes from market research website, Research and Markets. The company evaluated malignant pleural mesothelioma incidence in seven countries to come up with an 11-year forecast. According to the research, the US, UK, Japan, and four European countries can expect declining rates of asbestos cancer through 2030. Those who do receive a pleural mesothelioma diagnosis may benefit from some of the same drugs that are helping lung cancer patients survive. Lung Cancer…