An international research study including patients from 11 countries may help reveal new and better ways to predict peritoneal mesothelioma prognosis. Right now, doctors use three primary criteria to determine peritoneal mesothelioma prognosis. Those are how much cancer was in the abdomen at the time of surgery, how complete the surgery was, and the tumor grade. But about 70 percent of people treated for peritoneal cancers like mesothelioma have recurrent disease. The goal of the new study is to find more prognostic factors. Knowing these factors could help doctors make better choices about which patients are most likely to benefit from cytoreductive surgery (CRS). The CRS/HIPEC Procedure for Mesothelioma Peritoneal mesothelioma occurs on the lining of the abdomen. Peritoneal mesothelioma … Continue reading Peritoneal Mesothelioma Prognosis: Searching for New Factors
Having adjuvant radiotherapy after surgery may not help mesothelioma patients live any longer according to researchers at Duke and Stanford Universities. Researchers used a database of pleural mesothelioma patients from Duke and a national registry to conduct the analysis. They compared the outcomes of patients who had radiation after surgery (adjuvant radiotherapy) with the outcomes of those who did not. While radiotherapy may help reduce mesothelioma symptoms for some patients, the results of the study suggest that it is unlikely to extend survival. Radiation for Mesothelioma and Its Symptoms Radiotherapy is a mainstay of cancer therapy for certain kinds of cancer. But the irregular shape and aggressive nature of mesothelioma tumors makes them less than ideal for radiation treatment. Pleural … Continue reading Adjuvant Radiotherapy May Not Lengthen Mesothelioma Survival, Study Shows
The best mesothelioma surgery is the one the patient can tolerate with the fewest serious side effects. That’s according to a new study from MD Anderson researchers. Their goal was to help settle the ongoing debate over which type of pleural mesothelioma surgery is most effective. Both EPP and P/D surgery are major operations. But one causes much more serious side effects than the other. So how do doctors and patients decide on the best mesothelioma surgery for their case? The new research suggests there may not be a definitive answer. Debate Over the Best Mesothelioma Surgery Pleural mesothelioma is an asbestos-linked cancer of the membrane around the lungs. During EPP (extrapleural pneumonectomy) surgery, doctors remove this membrane, any other … Continue reading Study Asks What is the Best Mesothelioma Surgery?
A mesothelioma treatment called NIPEC may help people with peritoneal mesothelioma live longer than expected. In some cases, much longer. A recent study of 74 peritoneal mesothelioma patients showed a combination of cytoreductive surgery (CRS), HIPEC, and NIPEC works better than CRS/HIPEC alone. The study comes from one of the country’s foremost medical authorities on peritoneal mesothelioma. Dr. Paul Sugarbaker runs the Peritoneal Surface Malignancy Program at Washington Cancer Institute in Washington, DC. Last year, Dr. Sugarbaker released results of a small study on NIPEC treatment for mesothelioma. Although that study included only six patients, the results were impressive enough to warrant further study. This year’s larger NIPEC study is even more promising for people fighting mesothelioma. Similarities and DIfferences … Continue reading NIPEC Treatment: Is This the Key to Long-Term Mesothelioma Survival?
The two major types of mesothelioma surgeries carry similar risk of death, according to a new study from cancer researchers in Japan. One surgery involves removing the diseased pleural lining and one of the lungs. The other surgery removes many of the same tissues but leaves the lungs intact. Surgeons around the world are divided as to which of these mesothelioma surgeries is best. Mesothelioma patients have more complications with lung-removing surgery. But some studies suggest it could lead to longer survival. The 4-year Japanese study included more than 600 patients. It suggests that the likelihood of dying is similar with either of these mesothelioma surgeries. Surgical Treatment of Pleural Mesothelioma Pleural mesothelioma is the most common type of asbestos … Continue reading Mesothelioma Surgeries Carry Similar Mortality Risk, Study Finds
A new French study contains some good news for people considering the CRS/HIPEC procedure for peritoneal mesothelioma. The CRS/HIPEC procedure combines surgical resection with localized chemotherapy. Its aim is to remove or destroy as many mesothelioma cells as possible in the abdomen. French researchers studied the evolution of the procedure over time. They discovered that it has improved. As a result, people with peritoneal cancers like malignant mesothelioma are living longer. Cytoreductive Surgery for Mesothelioma Peritoneal mesothelioma causes tumors on the peritoneal membrane that lines the abdomen. Like other forms of mesothelioma, the cause is usually asbestos exposure. Cytoreductive surgery (CRS) is an operation to remove tumors from the abdomen. Mesothelioma tumors may be confined to the peritoneal membrane, or … Continue reading CRS/HIPEC Procedure Has Improved Over Time, Study Finds
A new study from the Icahn School of Medicine at Mount Sinai in New York suggests that minimally invasive surgery for mesothelioma is a “viable alternative” to open-chest procedures. Both of the two main surgical procedures for pleural mesothelioma are usually done through a large incision in the chest. Both procedures also carry a high risk of post-surgical complications. But the New York researchers found that minimally invasive surgery for mesothelioma may produce fewer serious problems in the short-term. It may also give mesothelioma patients a better quality of life after surgery. Surgical Treatment of Pleural Mesothelioma Pleural mesothelioma tumors occur on tissue that surrounds the lungs. These tumors tend to spread out across the tissue in irregular shapes. Their … Continue reading Minimally Invasive Surgery for Mesothelioma is “Viable Alternative” to Standard Approaches
It is not always possible to predict which patients will suffer from mesothelioma surgery complications. But a new study suggests there is way to make an educated guess about one particular kind of complication. A lung-removing operation called EPP used to be the preferred surgery for pleural mesothelioma. Most surgeons now favor a more conservative procedure called P/D. But surgeries do not always work out the way patients and surgeons hope they will. In some cases, mesothelioma surgery complications require the surgeon to convert a planned P/D procedure into an EPP operation instead. A team of Japanese researchers recently analyzed which patients had the highest risk for these mesothelioma surgery complications and what kinds of outcomes they experienced. Converting P/D … Continue reading Some Mesothelioma Surgery Complications May be Predictable
Another study is out and there is still no clear answer about the value of the SMART protocol for mesothelioma. SMART stands for surgery for mesothelioma after radiotherapy. After studying nearly a hundred patients, doctors in Toronto say radical surgery after RT can be effective. But they also say it is still very hard to prevent serious complications, even in an experienced center like theirs. The team at Princess Margaret Cancer Center tested the SMART protocol on previously-untreated pleural mesothelioma patients. As with previous studies of the SMART protocol for mesothelioma, some of the patients did very well. Many lived longer than they would normally expect to live. But there was also a high incidence of serious surgery-related complications. The … Continue reading Still No Clear Answer on SMART Protocol for Pleural Mesothelioma
CT scans are not a reliable way to detect the spread of mesothelioma into certain lymph nodes between the ribs. This is important because people with mesothelioma cells in their posterior intercostal lymph nodes (PILN) do not tend to get good results from P/D surgery. Surgeons need a good way to find mesothelioma cells in these lymph nodes before they decide to perform this risky operation. But University of Pennsylvania researchers say CT scans are not the best method. CT Scans in Mesothelioma Diagnosis and Prognosis CT stands for computerized tomography. A CT machine uses a series of X-ray images from different angles to create a 3D picture of a mesothelioma tumor. Most hospitals have a CT scanner. They are … Continue reading CT Scans Fail To Identify Metastatic Mesothelioma Prior to Surgery