Tag Archives: survival

Radiotherapy for Mesothelioma Doubles Survival in New Study

Radiotherapy for mesothelioma

Italian researchers presenting at an international conference this week say the right kind of radiotherapy for mesothelioma can dramatically boost survival. Radiation oncologist Marco Trovo and his colleagues at the University Hospital of Udine conducted the new mesothelioma research. They studied 108 pleural mesothelioma patients whose tumors could not be completely removed with surgery. Pleural mesothelioma affects the membrane around the lungs and is usually fatal within a year. But in the new study, more than half of the patients who had high doses of targeted radiotherapy in just the right area were still alive two years later. In contrast, just over a quarter of the patients who had palliative radiotherapy for mesothelioma lived to two years. Curative Versus Palliative … Continue reading Radiotherapy for Mesothelioma Doubles Survival in New Study »

Many Elderly Mesothelioma Patients Get No Treatment

elderly mesothelioma patients

The majority of elderly mesothelioma patients are observed rather than treated and this can have a negative impact on their survival. That is the finding of a new study published in the Annals of Surgical Oncology. The study included more than 4,500 mesothelioma patients. Less than a quarter of these patients received any treatment for their mesothelioma. As a result, most of these patients lived less than six months. Treatment Options for Elderly Mesothelioma Patients Exposure to asbestos causes pleural mesothelioma. It can take decades after exposure for mesothelioma symptoms to occur. The median age for a malignant pleural mesothelioma diagnosis is 72. The older a patient is at diagnosis, the more likely they are to have other health problems. … Continue reading Many Elderly Mesothelioma Patients Get No Treatment »

Lower-Volume Centers Less Likely to Follow Mesothelioma Treatment Guidelines

mesothelioma treatment guidelines

Mesothelioma patients need to beware of low-volume centers that are less likely to follow mesothelioma treatment guidelines. That is the message from a new study based on data from the National Cancer Institute. The study was run by doctors at Cedars-Sinai Medical Center in Los Angeles. It shows that treatment centers that do not see a lot of mesothelioma cases are less likely to follow the life-saving mesothelioma treatment guidelines. As a result, patients treated in these lower-volume facilities tend to have shorter mesothelioma survival. What are the Mesothelioma Treatment Guidelines? Malignant pleural mesothelioma is a cancer that occurs on the membrane that surrounds the lungs. It is extremely rare and difficult to treat. Many hospitals and doctors never see … Continue reading Lower-Volume Centers Less Likely to Follow Mesothelioma Treatment Guidelines »

Metastatic Mesothelioma: Does Chemotherapy Work?

metastatic mesothelioma

New research out of Pennsylvania suggested that not all people with metastatic mesothelioma will live longer with chemotherapy. Although chemotherapy is the primary treatment for malignant pleural mesothelioma, some types of metastatic mesothelioma appear to be less responsive than others. In some cases, the researchers say best supportive care may be a better option for preserving a patient’s quality of life. Three Mesothelioma Subtypes There are three histological subtypes of malignant pleural mesothelioma. The categories are based on how the cells look under a microscope. Cell type appears to influence how aggressive they are as metastatic mesothelioma. Cell type also factors into mesothelioma prognosis. Epithelioid mesothelioma is the most common cell type. Epithelioid cells tend to lack uniformity and may … Continue reading Metastatic Mesothelioma: Does Chemotherapy Work? »

Study Highlights How Genes Impact Mesothelioma Survival

Genes impact mesothelioma survival

A new National Cancer Institute study shines a light on some of the ways genes impact mesothelioma survival. It could have important implications for mesothelioma treatment. The study was led by prominent mesothelioma researcher Raffit Hassan, MD. It focused on genetic mutations that may make certain mesothelioma patients more sensitive to chemotherapy. Genes, Genotype, and Mesothelioma Treatment A mesothelioma patient’s unique collection of genes, including genetic mutations, is known as their genotype. Genes impact mesothelioma survival in a variety of ways. Tumor suppressor genes are supposed to help keep tumors from forming. People with mutations on these genes may be more likely to get malignant mesothelioma. Other genes influence the cancer’s ability to “hide” from detection by the immune system. … Continue reading Study Highlights How Genes Impact Mesothelioma Survival »

New Tool Could Replace TNM for Predicting Pleural Mesothelioma Survival

pleural mesothelioma survival

A new visual tool could offer a better way to predict pleural mesothelioma survival after surgery than the current TNM staging system. That is the message from cancer researchers at China’s Peking University. The group conducted a study using a large US government database of information on pleural mesothelioma survival and treatment. They used the data to create a visual representation of pleural mesothelioma survival called a nomogram. Testing of the nomogram showed it was more accurate at predicting survival in patients who have mesothelioma surgery than the tool doctors normally use. Pleural Mesothelioma Survival and TNM The most popular method for “staging” cancer is called the TNM staging system. TNM stands for tumor node metastasis. With TNM, the further … Continue reading New Tool Could Replace TNM for Predicting Pleural Mesothelioma Survival »

Study Reveals Mesothelioma Chemotherapy May Be Underused in Older Patients

mesothelioma chemotherapy treatment

The older a mesothelioma patient is, the less likely he or she may be to receive mesothelioma chemotherapy. A new study says many older mesothelioma sufferers may be paying the price in shorter lifespans. Chemotherapy with pemetrexed (Alimta) and cisplatin is the gold standard for mesothelioma treatment. Many studies have linked it with longer mesothelioma survival. But an Australian study suggests that not enough older people are receiving mesothelioma chemotherapy. In fact, the older they are, the less likely they are to have chemotherapy for their mesothelioma. As a result, their chances of dying from malignant mesothelioma are higher. Mesothelioma Chemotherapy is Standard of Care Malignant mesothelioma is a hard-to-treat cancer with a poor prognosis. Mesothelioma chemotherapy is the primary … Continue reading Study Reveals Mesothelioma Chemotherapy May Be Underused in Older Patients »

Longer Mesothelioma Survival Possible with Long-Term Local Chemotherapy

longer mesothelioma survival

There is evidence that repeatedly rinsing the abdomen with medicine might lead to longer mesothelioma survival after surgery. A rinse of heated chemotherapy drugs during surgery has become standard of care for peritoneal mesothelioma. Unfortunately, mesothelioma usually comes back. But a top mesothelioma doctor says longer mesothelioma survival might be possible if patients got regular chemotherapy “rinses” through a catheter. Studies show the drugs may not even have to be heated to work. Longer Mesothelioma Survival After Surgery Peritoneal mesothelioma is a type of asbestos cancer. It starts on the lining around the abdomen and can spread to other parts of the body. About a fifth of mesothelioma patients have this type. Heated intraperitoneal chemotherapy (HIPEC) has led to longer … Continue reading Longer Mesothelioma Survival Possible with Long-Term Local Chemotherapy »

Conservative Surgery Leads to Better Mesothelioma Survival After Recurrence

mesothelioma survival

Mesothelioma survival after recurrence may be better with lung-preserving P/D surgery than with more radical EPP. Japanese researchers recently analyzed the cases of 44 mesothelioma patients who underwent either EPP or P/D. It took about the same amount of time for mesothelioma tumors to start growing again, no matter what type of surgery the patient had. The difference was in survival. Both overall survival and mesothelioma survival after recurrence were longer in the P/D patients. EPP vs. P/D: The Ongoing Debate Mesothelioma surgeons around the world are still divided about which type of mesothelioma surgery is best. On one hand, extrapleural pneumonectomy (EPP) removes more diseased tissue, including a lung. Some say this improves the odds of long term mesothelioma … Continue reading Conservative Surgery Leads to Better Mesothelioma Survival After Recurrence »

Mesothelioma Survival Factors Revealed by New Study

mesothelioma survival factors

New research from the University of Pittsburgh reveals six primary mesothelioma survival factors. These characteristics appear to separate those who die of mesothelioma within just a few months from those who live much longer. The research focused on 888 cases of pleural or peritoneal mesothelioma listed in a national database. Patients received their mesothelioma diagnosis between 1990 and 2017. The study shows that most mesothelioma survival factors are out of patients’ control. Calculating Mesothelioma Survival Factors Not many people survive mesothelioma long term. It is one of the most aggressive and hard-to-treat types of cancer. By the time mesothelioma patients develop their first symptoms, the asbestos cancer is usually already at an advanced stage. Deciding the best way to treat … Continue reading Mesothelioma Survival Factors Revealed by New Study »