Long Term Peritoneal Mesothelioma Survival with NIPEC
| | | | |

Long Term Peritoneal Mesothelioma Survival with NIPEC

ByAlex Strauss

A new report suggests that long term peritoneal mesothelioma survival may be possible with a treatment called NIPEC and the drug paclitaxel.  NIPEC stands for normothermic intraperitoneal chemotherapy. It is similar to the heated chemotherapy that many peritoneal mesothelioma patients now get. But NIPEC is delivered through a catheter over time and at room temperature.  The new article details the long term peritoneal mesothelioma survival of six patients on NIPEC with paclitaxel. It comes from one the nation’s leading experts in this form of mesothelioma, Paul Sugarbaker, MD.  Even though the sample size is small, Dr. Sugarbaker says the results are impressive enough to warrant further study.  HIPEC and Mesothelioma Treatment Peritoneal mesothelioma accounts for about 20 percent of mesothelioma…

Odds of Surviving Mesothelioma Equal in Rural and Urban Australia
| | |

Odds of Surviving Mesothelioma Equal in Rural and Urban Australia

ByAlex Strauss

Living in a city and having a better socioeconomic status does not necessarily increase the odds of surviving mesothelioma.  That is the message from a 15-year Australian study of more than 300,000 cancer patients.  Some studies suggest cancer survival rates are lower in rural areas. But that does not appear to be the case for mesothelioma in Australia.  Unfortunately, the odds of surviving mesothelioma remain low no matter where a person lives. The Legacy of Asbestos in Australia Australia used to mine and export more asbestos than any other country. The mineral has been banned there since 2003, but Australian mesothelioma rates are still among the highest in the world.  Asbestos fibers are biopersistent. Once they are embedded in the…

Researchers Argue Against Surgery for Mesothelioma
| |

Researchers Argue Against Surgery for Mesothelioma

ByAlex Strauss

A pair of California surgeons say surgery for mesothelioma is rarely worthwhile. They point to what they say are flawed studies on surgical treatment. One trial they believe was well-conducted seems to show reduced mesothelioma survival after surgery. Writing in the journal Translational Lung Cancer Research, the doctors argue that most patients should choose non-surgical treatment for mesothelioma.  Some Background on Surgery for Mesothelioma Pleural mesothelioma is a cancer of the lining around the lungs. It is an aggressive cancer with no known cure. There are two primary approaches to surgery for mesothelioma. Both types are controversial and the subject of much debate among surgeons.  Extrapleural pneumonectomy (EPP) is a surgical approach that involves removing the pleural membrane, one lung,…

Surgery Extends Survival for Patients with Pleural Mesothelioma
| | | |

Surgery Extends Survival for Patients with Pleural Mesothelioma

ByAlex Strauss

Patients with pleural mesothelioma who choose to have surgery live longer than those who do not. This applies no matter which kind of surgery they have.  That is the conclusion of a Mexican study published in the Annals of Oncology. Doctors with the country’s National Institute for Respiratory Diseases conducted the study. It included 122 pleural mesothelioma patients.  The researchers analyzed a wide range of variables like age, sex, asbestos exposure, and overall health. They discovered that the decision to have surgery was one of the most important survival factors in patients with pleural mesothelioma. Treatment Options for Patients with Pleural Mesothelioma Pleural mesothelioma is an aggressive cancer with no known cure. It usually occurs in people who have been…

Radical Surgery for Peritoneal Mesothelioma Boosts Survival
|

Radical Surgery for Peritoneal Mesothelioma Boosts Survival

ByAlex Strauss

Patients who have radical surgery for peritoneal mesothelioma live longer than those who have non-surgical treatments.  That is the conclusion of a team of Virginia researchers. The study is based on peritoneal mesothelioma cases in the National Cancer Database. It spans more than a decade and includes over 2,000 patients.  Not everyone is a candidate for radical surgery for peritoneal mesothelioma. But the research shows that those who have surgery live an average of five times longer than those who do not.  Surgical Treatment of Peritoneal Mesothelioma Peritoneal mesothelioma is sometimes called diffuse malignant peritoneal mesothelioma. It is an aggressive cancer in the abdomen. It grows on the membrane around organs. Because mesothelioma tumors lie so close to these organs,…

Repeated Mesothelioma Surgeries Credited with Japanese Man’s Survival
| | |

Repeated Mesothelioma Surgeries Credited with Japanese Man’s Survival

ByAlex Strauss

Can repeated mesothelioma surgeries extend peritoneal mesothelioma survival? A new case report out of Japan suggests the answer may be yes.  The article recounts the case of a patient with peritoneal mesothelioma. Each time surgeons removed a mesothelioma tumor, a new one would occur in a different location.  The man had four separate mesothelioma surgeries over the course of five years.  Repeated mesothelioma surgeries are not the norm. But this treatment approach may be the reason for the man’s unusually long mesothelioma survival.  Surgical Treatment of Peritoneal Mesothelioma Peritoneal mesothelioma accounts for about 20 percent of mesothelioma cases in the US each year. It occurs on the membrane that surrounds the abdominal organs. Because it sits so close to these…

Should Mesothelioma Patients Take Aspirin for Cancer Survival?
| | |

Should Mesothelioma Patients Take Aspirin for Cancer Survival?

ByAlex Strauss

There is new evidence supporting the use of low-dose aspirin for cancer survival.  The evidence comes from two new retrospective studies. The first involved patients with head and neck cancer. The second focused on patients with early-stage non-small cell lung cancer (NSCLC). NSCLC is similar to mesothelioma in many ways.  Mesothelioma is an aggressive cancer that is often fatal within a year of diagnosis. Based on the new findings, some mesothelioma patients may consider talking to their doctors about aspirin for cancer survival Anti-Inflammatories and Cancer Treatment Anti-inflammatory drugs like aspirin can cut the risk for heart disease and heart attack. But research led by the Roswell Park Cancer Center shows they may have similar benefits for people with cancers…

Talc Pleurodesis for Mesothelioma May Extend Survival
| | |

Talc Pleurodesis for Mesothelioma May Extend Survival

ByAlex Strauss

A UK study suggests that successful talc pleurodesis for mesothelioma improves survival better than other lung fluid treatments.  Researchers in Oxford’s Chest Diseases Department analyzed the outcomes of two groups of pleural mesothelioma patients. Both groups underwent talc pleurodesis for mesothelioma.  The patients whose lung fluid did not come back after treatment experienced longer survival. Mesothelioma patients who had to be retreated did not live as long.  Pleural Effusion in Mesothelioma The pleura is a membrane that surrounds and encases the lungs. It is supposed to be flexible and allow the lungs to move when a person breathes.  But patients with pleural mesothelioma often develop pleural effusion. Pleural effusion is a build-up of excess fluid in the space between the…

First-Line Keytruda Treatment May Support Longer Mesothelioma Survival
| | | |

First-Line Keytruda Treatment May Support Longer Mesothelioma Survival

ByAlex Strauss

New data suggests first-line Keytruda treatment helps lung cancer patients more than chemotherapy – even if chemotherapy patients add Keytruda later. The news is likely to have implications for people with pleural mesothelioma, too. German researchers presented the data earlier this week at the World Lung Cancer Conference in Barcelona.  The presentation was based on three years of the KEYNOTE-024 trial. The trial focused on lung cancer. But Keytruda is also an up-and-coming drug for malignant pleural mesothelioma. Pleural mesothelioma is a lung-related cancer similar to non-small cell lung cancer.  Blocking PD-L1 with First-Line Keytruda Treatment Keytruda is the brand name for pembrolizumab. It is an immune checkpoint inhibitor that blocks a protein called PD-L1. To be eligible for first-line…

Pleural Mesothelioma Rates Remain Stagnant As Survival Improves
| | |

Pleural Mesothelioma Rates Remain Stagnant As Survival Improves

ByAlex Strauss

A new report shows pleural mesothelioma rates in the US have failed to decline as they were predicted to do, but survival is improving slightly.  The US government began to implement tighter restrictions on asbestos in the 1970s. Researchers at the Cleveland Clinic say original projections had the incidence of pleural mesothelioma peaking in the early 2000s as a result. Pleural mesothelioma rates were supposed to decline after that. But numbers from the National Cancer Database (NCDB) tell a different story. They suggest that, while mesothelioma survival is improving, incidence of asbestos cancer are not. Asbestos and Malignant Mesothelioma Malignant mesothelioma is the most serious of a range of illnesses caused by asbestos. Pleural mesothelioma is the most common type…