Vitamin E Analog Inhibits Blood Vessel Growth in Mesothelioma Cells
Scientists say a form of Vitamin E may be able to help fight malignant mesothelioma by limiting the growth of tumor-feeding blood vessels. Researchers with Toyo University’s Graduate School of Life Sciences in Japan recently released a study on the redox-silent tocotrienol (Vitamin E) analog 6-O-carboxypropyl-α-tocotrienol – called T3E – and its impact on mesothelioma. Although previous studies have found T3E to have powerful anti-cancer properties, the goal of the new study was to better understand its mechanism in mesothelioma cells. According to a report in Biological and Pharmaceutical Bulletin, T3E worked against mesothelioma cells by inhibiting the expression of vascular endothelial growth factor (VEGF), a signaling protein that supplies fresh oxygen to cells by stimulating the growth of new…