Searching for New Mesothelioma Drugs Among African Plants

Doctors in Cameroon and Turkey say two types of African plants deserve more study as potential treatments for malignant mesothelioma and other intractable cancers. The plants, including Elephantopus mollis,, Kalanchoe crenata, and four other medicinal plants, contain compounds that triggered cell death when tested on mesothelioma cells in the laboratory. At present, there is no cure for mesothelioma and no drugs that consistently slow its progression. Even the most powerful anti-cancer drugs in use today typically have only a modest effect on this aggressive asbestos-linked malignancy. Testing Plant Extracts on Mesothelioma Tumor Cells For their new study, scientists at two Cameroonian universities and Anadolu University in Turkey utilized the methanol extracts from the whole Elephantopus mollis plant (EMW), the bark … Continue reading Searching for New Mesothelioma Drugs Among African Plants »

African Plants May Offer New Ways to Treat Mesothelioma

Could compounds found in African plants hold the key to fighting intractable malignant mesothelioma? That is the suggestion of a new study conducted by an international team of researchers including scientists in Cameroon and Kenya. The study published in a recent issue of BMC Pharmacology and Toxicology, focused on naturally occurring quinones, organic compounds found in bacteria, certain fungi, and in various plants, including some found in Kenya. Quinones as Cancer Fighters The new study focused on 14 different naturally occurring quinones including three in the group anthraquinones, one naphthoquinone and ten benzoquinones. The substances were tested on six types of cancer cells, including malignant mesothelioma, as well as on normal connective tissue cells called fibroblasts. Specifically, the researchers were … Continue reading African Plants May Offer New Ways to Treat Mesothelioma »

The Link Between Malignant Mesothelioma and Other Cancers

If you have malignant mesothelioma, evidence suggests that you have a higher-than-normal risk of also developing another type of cancer, either before or after your mesothelioma diagnosis. The research was carried out by a team of international scientists who examined the cases of more than 5,000 mesothelioma patients around the world. Second Primary Cancers After Mesothelioma In the first study of both secondary cancers after mesothelioma, and vice versa, the team first looked at cancer that developed after mesothelioma in 3,672 survivors of pleural mesothelioma and 895 peritoneal mesothelioma survivors. Among these patients, they found a higher incidence of kidney cancer within a year after a mesothelioma diagnosis. For all other cancers, although the incidence was still higher than normal, … Continue reading The Link Between Malignant Mesothelioma and Other Cancers »

Clinical Trial May be Best Second-Line Approach for Mesothelioma

Doctor holding x-ray film

The best second-line treatment for mesothelioma patients who fail to respond to standard chemotherapy is probably to enroll in a clinical trial. The authors of a newly-published paper on the subject reached that conclusion after reviewing the results of 29 studies on potential second- or third-line mesothelioma treatments. Most patients who are diagnosed with mesothelioma, an aggressive malignancy associated with asbestos exposure, will undergo chemotherapy, either as a stand-alone treatment or as part of a multimodal approach. Unfortunately, only a small percentage of mesothelioma patients treated with standard pemetrexed/cisplatin chemotherapy will show a response. Even those who respond to chemotherapy often relapse again later. Scientists around the world are searching for new drugs and drug combinations to offer mesothelioma patients … Continue reading Clinical Trial May be Best Second-Line Approach for Mesothelioma »

New Study Helps Explain How Asbestos Leads to Mesothelioma

asbestos ban

New research suggests that tiny proteins called cytokines may be to blame for much of the destruction caused by asbestos in the body. Asbestos is the top cause worldwide of malignant pleural mesothelioma, a rare but difficult-to-treat cancer that often kills patients within a year of diagnosis. When they are inhaled, asbestos fibers lodge in the lugs triggering irritation and inflammation that eventually causes cells to become malignant. But the exact mechanism that moves cells from irritation to mesothelioma is still poorly understood. Now, researchers in Brazil have uncovered another piece of the puzzle that may help explain how mesothelioma develops. According to a new published report, they have isolated two small signaling proteins called cytokines that appear to be … Continue reading New Study Helps Explain How Asbestos Leads to Mesothelioma »

Italian Report Details “Global Mesothelioma Epidemic”

Two Italian researchers say mesothelioma has reached epidemic proportions in some parts of the world and does not appear to be slowing down any time soon. In a new report in the Indian Journal of Occupational and Environmental Medicine, Claudio and Tommaso Bianchi of the Center for the Study of Environmental Cancer in Monfalcone, Italy analyzed data from cancer registries around the world. They supplemented their raw data with information they got from mesothelioma researchers in other countries. What they found was a disturbing upward trend in mesothelioma incidence in several European countries, as well as in Australia and New Zealand. According to the Bianchis, the UK, The Netherlands, Malta and Belgium reported the highest number of mesothelioma cases in … Continue reading Italian Report Details “Global Mesothelioma Epidemic” »

Brief, Indirect Exposure Leads to Mesothelioma in Young Woman

asbestos ban

A new report contains some disturbing news about just how little asbestos exposure it may take to cause malignant mesothelioma. Radiologists in New Delhi, India have published details of a case of mesothelioma in a young woman who experienced only very limited asbestos exposure as a child. According to the article in the Journal of Clinical Imaging Science, the young woman was diagnosed with malignant pleural mesothelioma after complaining of chest pain and breathlessness. X-rays and CT scans revealed that, not only was she suffering from the asbestos cancer, but that it had also spread to her liver and lungs. A biopsy of one of the tumors confirmed the diagnosis. In addition to being much younger than most mesothelioma patients, … Continue reading Brief, Indirect Exposure Leads to Mesothelioma in Young Woman »

Studies Highlight Global Mesothelioma and Asbestos Problem

Two new reports highlight the fact that mesothelioma and other asbestos-related diseases are global issues. Reporting in a recent issue of Global Health Action, scientists from South Africa’s National Institute for Occupational Health and the University of Witwatersrand in Johannesburg say the country is facing an epidemic of environmentally-linked asbestos-related diseases like mesothelioma because of abandoned asbestos mines. The same report also found that many of these mesothelioma patients are not receiving any compensation for their injuries. South Africa was once a top exporter of asbestos, which was used for thousands of industrial applications, including insulation, construction materials, asbestos cement, and friction products like brake and clutch pads. Although all of South Africa’s asbestos mines are now closed because of the … Continue reading Studies Highlight Global Mesothelioma and Asbestos Problem »

Pakistan May Ban Asbestos to Reduce Mesothelioma

Pakistan may be on the brink of banning the leading cause of mesothelioma. The mineral asbestos, used for decades in various industries, is believed to be responsible for nearly all cases of mesothelioma, an intractable cancer of the linings around organs. Now, the National Assembly’s Standing Committee on Human Resource Development in Pakistan is recommending that the use and importation of asbestos be permanently banned in the country. The committee made the recommendation after a series of hearings on asbestos and its link to mesothelioma. Federal Human Resource Secretary Raja Ahsan told the committee that asbestos presents a “major threat” for mesothelioma and cancer among Pakistan’s industrial workers. Asbestos consumption continues to rise in Pakistan; One study shows that the figure … Continue reading Pakistan May Ban Asbestos to Reduce Mesothelioma »

Mesothelioma Not Enough to Blacklist Asbestos

The 141 member nations of the international Rotterdam Convention have once again failed to add asbestos to their list of banned chemicals, much to the disappointment of mesothelioma patients, doctors and researchers worldwide. Asbestos has long been linked to the deadly cancer mesothelioma. It causes an estimated 2,500 new cases of mesothelioma in the U.S. each year and tens of thousands of cases elsewhere in the world.  According to the World Health Organization (WHO), about 125 million people are exposed to asbestos in the workplace and more than 107,000 die each year from mesothelioma and other asbestos-related diseases.  Although the mineral is now regulated (though not banned) in the U.S., many third-world countries use it as a cheap building material with little … Continue reading Mesothelioma Not Enough to Blacklist Asbestos »

Get your free copy of
“Surviving Mesothelioma” Today!