Tag Archives: immune system

Long Term Mesothelioma Survival with Immune System Activation

A small group of Australian mesothelioma patients have reportedly lived more than twice as long as expected with a combination of standard chemotherapy and immune system manipulation with the CD40 protein. The CD40 protein plays a role in a broad range of immune and inflammatory responses in the body. Studies in mice have found that activating CD40 with an activating antibody may work “synergistically” with chemotherapy drugs to fight cancer. To see whether CD40 activation could produce a similar response in human patients, researchers with the University of Western Australia and Sir Charles Gairdner Hospital in Perth recruited 15 malignant pleural mesothelioma patients in the early stages of the disease. The patients all received both standard chemotherapy (pemetrexed and cisplatin) … Continue reading Long Term Mesothelioma Survival with Immune System Activation »