Tag Archives: IMRT

Radiotherapy Before Mesothelioma Surgery May Not Be Worth the Risk

Radiotherapy before mesothelioma surgery

Cancer doctors at Mayo Clinic say they do not plan to start routinely performing radiotherapy before mesothelioma surgery. The idea is based on a radiation protocol called SMART. The team monitored how well the SMART protocol worked among their pleural mesothelioma patients over a one year period.  The Mayo doctors acknowledged that radiotherapy before mesothelioma surgery can sometimes improve outcomes. But too many of their patients developed serious complications. In a recently-published article, the team concludes that SMART may not be worth the risk for most patients.  The SMART Way to Treat Mesothelioma? Pleural mesothelioma grows on the membrane that surrounds the lungs. Mesothelioma tumors lie close to the lungs and heart and may spread to one or both lungs. … Continue reading Radiotherapy Before Mesothelioma Surgery May Not Be Worth the Risk »

Targeted Radiotherapy for Mesothelioma May Extend Survival in the Right Patients

targeted radiotherapy for mesothelioma

A meta-analysis conducted by some of the country’s top cancer researchers says targeted radiotherapy for mesothelioma can help some people live longer. It is the first such analysis of targeted radiation after lung-sparing mesothelioma surgery. The team focused on intensity modulated radiation therapy (IMRT). IMRT is more precise than earlier forms of radiation treatment.  The new article appears in Practical Radiation Oncology. It is a meta-analysis of ten smaller studies. The researchers conclude that healthier surgery patients could safely consider targeted radiotherapy for mesothelioma. Making Radiotherapy Less Toxic In the past, radiation for mesothelioma has sometimes done more harm than good. Earlier types of radiation treatment were not as precise as IMRT. When radiation spills over into healthy tissue, it … Continue reading Targeted Radiotherapy for Mesothelioma May Extend Survival in the Right Patients »

Study Supports Curative Radiation Therapy for Pleural Mesothelioma

radiation therapy for pleural mesothelioma

A new study out of Turkey supports the idea of using highly targeted radiation therapy for pleural mesothelioma that can’t be treated surgically. Pleural mesothelioma is a cancer that grows on the membrane around the lungs. The membrane is called the pleura. Like all forms of mesothelioma, it carries a grim prognosis. But the Turkish researchers say new radiotherapy techniques offer the promise of better outcomes. They compared two types of radiation therapy for pleural mesothelioma. They found that both could be delivered safely and with limited damage to nearby organs.  Unrectable Pleural Mesothelioma The first-line treatment for pleural mesothelioma is chemotherapy. Ideally, chemotherapy will help to shrink the pleural mesothelioma. Then doctors can remove most of it surgically. They … Continue reading Study Supports Curative Radiation Therapy for Pleural Mesothelioma »

IMRT for Mesothelioma: Barriers to Completing Treatment

PD-L1 inhibitor nivolumab

MD Anderson researchers say too many patients who might benefit from IMRT for mesothelioma never complete the treatment. The problem could be impacting their survival. Intensity Modulated Radiotherapy (IMRT) is a type of targeted radiation. It is designed to direct as much radiation as possible into the mesothelioma tumor without harming the surrounding tissue.  Patients who have a combination of surgery, chemotherapy, and IMRT for mesothelioma have the best odds of survival. But at MD Anderson Cancer Center, only two thirds of eligible patients completed IMRT after mesothelioma surgery. The new study aimed to find out why. Trimodal Therapy and Mesothelioma Survival Malignant mesothelioma rarely responds to a single cancer therapy. Trimodal therapy combines several different treatments to maximize success.  … Continue reading IMRT for Mesothelioma: Barriers to Completing Treatment »

IMRT for Long-Term Survival After Mesothelioma Surgery

Intensity modulated radiation therapy (IMRT) can safely slow or even stop mesothelioma progression after surgery as long as the dose is just right. A team of Texas radiation oncologists reached that conclusion after studying the treatment results of 18 mesothelioma patients between 2005 and 2014. IMRT is a highly targeted form of high-dose radiation. While it can have a powerfully negative effect on tumor cells, it can also have an equally negative effect on healthy lung tissue. Some patients have even died from pulmonary toxicity caused by IMRT. But in a report published in the journal Oncology, doctors from Texas A & M Medical Sciences Center and Baylor Scott and White Hospital found that, as long as the radiation dose … Continue reading IMRT for Long-Term Survival After Mesothelioma Surgery »

Mesothelioma Outcomes May Be Improved by New Radiation Therapy

There is evidence that a new type of radiation therapy may have advantages over other methods for treating mesothelioma patients after surgery. A marriage of spiral CT-scanning technology and intensity modulated radiation therapy (IMRT), helical tomotherapy offers enhanced precision and the ability to ‘sculpt’ the radiation dose to conform to the size and shape of the tumor being treated. Because mesothelioma tumors tend to be irregular in shape and spread out across the membranous mesothelial tissue, this sculpting ability may help doctors deliver just enough post-surgical radiation to kill remaining cancer cells without damaging large numbers of healthy cells. In a recent study on the technology at the University of Paris, a group of French researchers analyzed the treatment outcomes … Continue reading Mesothelioma Outcomes May Be Improved by New Radiation Therapy »