Tag Archives: molecular pathways

Sarcomatoid Mesothelioma Treatment Focuses on Two-Drug Combo

sarcomatoid mesothelioma treatment

Researchers in Spain are developing what they hope will be a more effective sarcomatoid mesothelioma treatment. The new treatment focuses on a pair of drugs that are already being tested in humans.  Mesothelioma impacts about 2,500 Americans each year. Sarcomatoid mesothelioma is a rare form of this rare cancer. About a quarter of the annual cases are sarcomatoid.  This form of cancer is even more aggressive than epithelioid mesothelioma. But sarcomatoid mesothelioma treatment is not significantly different. Neither are the results.  But the new study could change the prognosis for people with asbestos cancer. It appears in the journal Cancer Research. Chemotherapy is the Primary Sarcomatoid Mesothelioma Treatment Most people with malignant mesothelioma receive chemotherapy with cisplatin and Alimta. This … Continue reading Sarcomatoid Mesothelioma Treatment Focuses on Two-Drug Combo »

Mesothelioma and Molecular Pathways

A recently published review* looks at some of the molecular signaling pathways currently being investigated in mesothelioma. The challenge of developing disease-specific treatments. The goal is to develop more – and more effective – treatments, says co-author Dan J. Raz, MD, of the University of California, San Francisco’s Division of Thoracic Surgery. “The options for mesothelioma patients have primarily been surgery, conventional chemotherapy, and radiation therapy,” Raz says. “But even when a combination of treatments is used, the outcomes aren’t great.” While several drugs have been approved for treating mesothelioma, there aren’t a lot – largely because researchers simply haven’t been able to conduct many clinical drug trials. This is in part because, with some 5,000 Americans diagnosed with the … Continue reading Mesothelioma and Molecular Pathways »