Two New Diagnostic Tissue Biomarkers Discovered for Mesothelioma
| | |

Two New Diagnostic Tissue Biomarkers Discovered for Mesothelioma

ByHolly Zink

Scientists have now identified two new diagnostic tissue biomarkers for malignant pleural mesothelioma. Doctors identify mesothelioma using diagnostic tissue biomarkers. This is called immunohistochemistry. The use of immunohistochemistry improves the accuracy of mesothelioma diagnosis in clinical practice. Yet, new methods for discovering diagnostic markers are still needed. Following a Reverse Approach in a Rare Case Mesothelioma is usually diagnosed after a person experiencing symptoms goes to a doctor. One thing a doctor may do is perform a tissue biopsy. The doctor will remove a part of the tissue (suspected mesothelioma) for examination. Most tissue biopsies are done with a needle and then examined in a laboratory. The lab will look for specific biomarkers to find out if the tissue contains…

New Biomarkers Could Mean Earlier, More Accurate Mesothelioma Diagnosis
| | |

New Biomarkers Could Mean Earlier, More Accurate Mesothelioma Diagnosis

ByAlex Strauss

In what could be a breakthrough in the development of a reliable diagnostic test for mesothelioma, Danish scientists have identified what they say are four key biomarkers that distinguish the asbestos cancer from non-malignant conditions. If the new research from Copenhagen University can be validated, it may dramatically shorten the time it takes to identify mesothelioma and start aggressive therapies. “Our goal was to identify microRNAs (miRNAs) that can aid in the differential diagnosis of MPM [malignant pleural mesothelioma] from RMPs [reactive mesothelial proliferations],” investigator Eric Santoni-Rugiu, MD, PhD, of the Laboratory of Molecular Pathology at Copenhagen University Hospital in Denmark said in a press release. MiRNAs are small cellular components that act as master switches for protein synthesis inside…