Unveiling the Rare: Pericardial and Peritoneal Mesothelioma

Unveiling the Rare: Pericardial and Peritoneal Mesothelioma

ByHolly Zink

Mesotheliomas are a rare type of cancer caused by exposure to asbestos. Mesothelioma in the lungs is called pleural mesothelioma and is the most common type. However, pericardial and peritoneal mesothelioma are even rarer forms. These types of mesothelioma grow in the heart and in the abdomen. A team of researchers from the United States wanted to learn more. They looked at patients who were hospitalized with these unusual types of cancer. Patients of Uncommon Mesothelioma Types They ran a study looking at patients with pericardial and peritoneal mesothelioma who went to the hospital from 2016 to 2020. They split the patients into two groups. First, those with pericardial mesothelioma. And second, those with peritoneal mesothelioma. The researchers looked at…

Breaking Ground in Peritoneal Mesothelioma Treatment
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Breaking Ground in Peritoneal Mesothelioma Treatment

ByHolly Zink

Researchers from Spain are trying to understand just how effective a multi-modal therapy is at treating mesothelioma in the abdomen. The treatment is called cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Or, CRS-HIPEC for short. Mesothelioma that is found in the abdomen is called peritoneal mesothelioma. It is caused by the ingestion of asbestos fibers. Those tiny asbestos fibers become stuck in the abdomen. After 20 to 50 years, these fibers can cause inflammation and mutations in the healthy cells in the abdomen. These mutations can cause these cells to form tumors in the abdomen. Patients diagnosed with MPM have longer life expectancy than those with other types of mesothelioma. Some studies report patients live up to 5 years after treatment….

Predicting Mesothelioma Survival with Advanced Techniques
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Predicting Mesothelioma Survival with Advanced Techniques

ByHolly Zink

A team of scientists is working on developing a way to predict the survival of mesothelioma patients. In particular, those who are treated with a specific type of surgery and chemotherapy. The prediction tool would work for patients with peritoneal mesothelioma. This is a type of mesothelioma that grows in the lining of the abdominal cavity. Peritoneal mesothelioma is caused by asbestos. Peritoneal mesothelioma occurs in less than 1,000 people in the United States every year. Most of these people are over the age of 65, but it can also develop in people who are much younger. Symptoms associated with peritoneal mesothelioma may take decades after asbestos exposure to appear. They are usually noticed first in the stomach or intestinal…

New Way to Identify Biopsy Sites to Diagnose Mesothelioma
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New Way to Identify Biopsy Sites to Diagnose Mesothelioma

ByHolly Zink

A study in Cancer Diagnosis and Prognosis explores a new way to identify biopsy sites to diagnose mesothelioma. Mesothelioma is an aggressive cancer caused by asbestos exposure. There are a few different types of mesothelioma. One type is malignant peritoneal mesothelioma. It is hard to diagnose peritoneal mesothelioma because its symptoms could also be caused by other diseases. It usually requires many tests to diagnose peritoneal mesothelioma. The delay in diagnosing peritoneal mesothelioma also delays treatment. The first diagnostic test is usually computed tomography (CT). CT scans are like a more sophisticated X-ray. The results of the CT scan help doctors locate the best place to conduct a biopsy. A biopsy is the examination of tissue to discover if the…

National Institutes of Health Reports on Advances in Malignant Peritoneal Mesothelioma
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National Institutes of Health Reports on Advances in Malignant Peritoneal Mesothelioma

ByHolly Zink

A new article from the National Institutes of Health gives the latest advances in mesothelioma. CRS-HIPEC has offered improved survival for surgical candidates. But outcomes for inoperable malignant peritoneal mesothelioma remain poor. Advancements in technology have provided new treatment approaches. The NIH reports new clinical trials are arising and are imperative. The Numbers Behind Peritoneal Mesothelioma Peritoneal mesothelioma is caused by exposure to asbestos. It is caused by the ingestion of asbestos fibers. Those microscopic asbestos fibers become embedded in the abdomen (peritoneum). After 20 to 50 years, these fibers can cause inflammation and mutations in the healthy mesothelial cells. These mutations can cause these cells to become cancerous thus, forming tumors in the peritoneum. Patients diagnosed with peritoneal mesothelioma…

Using CT Scans in Surgical Decision-Making in Peritoneal Mesothelioma
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Using CT Scans in Surgical Decision-Making in Peritoneal Mesothelioma

ByHolly Zink

Peritoneal mesothelioma is caused by asbestos. The peritoneum is the space in your abdomen that contains the intestines, the stomach, and the liver. The abdomen (peritoneum) is the second most common site of mesothelioma after the pleural (lungs and chest). Most doctors believe peritoneal mesothelioma is caused by the ingestion of asbestos fibers. Microscopic asbestos fibers become embedded in the abdomen (peritoneum). After about 20-50 years, these fibers can cause inflammation and mutations in the healthy mesothelial cells. These mutations may ultimately cause these cells to become cancerous. Thus, forming tumors in the peritoneum. Patients diagnosed with peritoneal mesothelioma may survive several or more years after diagnosis. There are long-term survivors, such as Paul Kraus. Using CT Scans to Avoid…

Korean Cancer Doctors Embrace PIPAC for Mesothelioma
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Korean Cancer Doctors Embrace PIPAC for Mesothelioma

ByAlex Strauss

Five out of ten Korean oncologists surveyed feel positive about using an aerosolized chemotherapy system called PIPAC for mesothelioma and other types of cancer. PIPAC stands for pressurized intraperitoneal aerosol chemotherapy. The system turns liquid chemotherapy drugs into a spray that can be applied with a nebulizer. It was developed to treat surface malignancies like peritoneal mesothelioma that can be hard to treat with standard methods.  PIPAC can be used in conjunction with mesothelioma surgery or by itself as either a palliative or curative treatment.  The technology is still very new. Many doctors have never used it. But research conducted by the Seoul National University College of Medicine shows Korean doctors are ready to embrace it. How Spray-on Chemotherapy Works…

Misdiagnosis of Mesothelioma More Common with Cytology Alone
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Misdiagnosis of Mesothelioma More Common with Cytology Alone

ByAlex Strauss

A new set of case reports illustrates how easily misdiagnosis of mesothelioma can happen when the diagnosis is based on cytology alone.  Cytology tests look at the cells in body fluids. For peritoneal mesothelioma patients, this is often the fluid that collects in their abdomen called ascites.  But doctors from India’s Dayanand Medical College and Hospital say using ascites samples alone to diagnose mesothelioma is a risky practice. Misdiagnosis of mesothelioma may delay proper treatment and negatively impact survival. The Difficulty of Diagnosing Peritoneal Mesothelioma Malignant mesothelioma only impacts about 2,500 people in the US every year. It is most common among people who have lived or worked around asbestos. Peritoneal mesothelioma is even rarer. About a fifth of patients…

New Surgical Technique May Support Long-Term Peritoneal Mesothelioma Survival
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New Surgical Technique May Support Long-Term Peritoneal Mesothelioma Survival

ByAlex Strauss

One of the nation’s top mesothelioma doctors says long-term peritoneal mesothelioma survival is possible with a far-reaching new surgical technique. Dr. Paul Sugarbaker is a surgeon with the Washington Cancer Institute in Washington, DC. He has studied peritoneal mesothelioma for decades.  In a new report, he outlines a case of long-term peritoneal mesothelioma survival in a female patient. The patient had cytoreductive surgery. The surgery included resection of the colonic mesentery. This is tissue that is not normally part of peritoneal mesothelioma surgery.  The case report shows the patient is still cancer-free four years after surgery with an “excellent” quality of life.  The Challenge of Peritoneal Mesothelioma Every year, about 2,500 Americans receive a diagnosis of mesothelioma. Peritoneal mesothelioma accounts…

New “Real World” Study of Immunotherapy for Peritoneal Mesothelioma
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New “Real World” Study of Immunotherapy for Peritoneal Mesothelioma

ByAlex Strauss

A new study from one of the nation’s top cancer centers supports the role of immunotherapy in peritoneal mesothelioma treatment. Immunotherapy is a treatment approach that aims to harness the body’s natural defense system to fight cancer.  Several immunotherapy drugs have been tested for pleural mesothelioma. Pleural mesothelioma affects the lungs. Last year, the FDA approved a new combination of immunotherapy drugs for the pleural form of asbestos cancer.  But there is less data on immunotherapy for peritoneal mesothelioma. Researchers at MD Anderson Cancer Center just released their findings on a class of immunotherapy drugs called immune checkpoint inhibitors (ICIs). They say it is the first “real-world evidence” of clinical outcomes with ICIs in peritoneal mesothelioma patients. Immune Checkpoint Inhibitors…