Tag Archives: peritoneal mesothelioma

Longer Mesothelioma Survival Possible with Long-Term Local Chemotherapy

longer mesothelioma survival

There is evidence that repeatedly rinsing the abdomen with medicine might lead to longer mesothelioma survival after surgery. A rinse of heated chemotherapy drugs during surgery has become standard of care for peritoneal mesothelioma. Unfortunately, mesothelioma usually comes back. But a top mesothelioma doctor says longer mesothelioma survival might be possible if patients got regular chemotherapy “rinses” through a catheter. Studies show the drugs may not even have to be heated to work. Longer Mesothelioma Survival After Surgery Peritoneal mesothelioma is a type of asbestos cancer. It starts on the lining around the abdomen and can spread to other parts of the body. About a fifth of mesothelioma patients have this type. Heated intraperitoneal chemotherapy (HIPEC) has led to longer … Continue reading Longer Mesothelioma Survival Possible with Long-Term Local Chemotherapy »

Researchers Name Six Top Mesothelioma Survival Factors

Certain factors lead to longer mesothelioma survival

Researchers at the University of Pittsburgh have named what they say are the top six mesothelioma survival factors. According to their new study, patients with one or more of these factors tend to have better mesothelioma treatment outcomes and live longer. Malignant mesothelioma – also called asbestos cancer – is one of the deadliest forms of cancer. It starts on internal membranes and spreads quickly. There is no cure and the disease is very hard to slow down. Many mesothelioma patients die within 12 to 18 months. But there are cases of much longer mesothelioma survival. Some patients have even lived for decades after mesothelioma treatment. The Pittsburgh researchers wanted to find the mesothelioma survival factors shared by the longest … Continue reading Researchers Name Six Top Mesothelioma Survival Factors »

Immunotherapy for Peritoneal Mesothelioma: New Drug Trial Begin

immunotherapy for peritoneal mesothelioma

Researchers in Maryland and Missouri have started human testing of a new type of immunotherapy for peritoneal mesothelioma. If the human trial of this new CAR T-cell therapy goes as well as the laboratory tests, this could be good news for many people with asbestos cancer. CAR stands for chimeric antigen receptor. CAR T-cell therapy works by “reprogramming” a patient’s immune system to fight cancer cells. Tests show this therapy can work well for blood-based cancers like leukemia. But the results have not been as good for solid tumors like peritoneal mesothelioma. MaxCyte is the American company than makes the new drug. They are hoping that their approach to immunotherapy for peritoneal mesothelioma will be better. Preparing CAR T-cell Therapy … Continue reading Immunotherapy for Peritoneal Mesothelioma: New Drug Trial Begin »

Extended Survival of Peritoneal Mesothelioma with Repeat Treatment

There is some good news on the research front for patients with recurrent peritoneal mesothelioma. Doctors at the University of New South Wales in Australia say that treating these patients again with surgery and heated chemotherapy is extending lives, sometimes for several years. Peritoneal mesothelioma, which accounts for about 20 percent of mesothelioma cases, occurs on the peritoneal membrane that surrounds abdominal organs. Cytoreductive surgery (CRS) aims to remove as much of that diseased tissue as possible. It is often followed by heated intraperitoneal chemotherapy (HIPEC) to kill any remaining mesothelioma cells and to keep new tumors from starting. The CRS/HIPEC combination has become the gold standard first line treatment for peritoneal mesothelioma. But the authors of a new study … Continue reading Extended Survival of Peritoneal Mesothelioma with Repeat Treatment »

Refining CRS-HIPEC for Peritoneal Mesothelioma

Surgery for Peritoneal Mesothelioma

  Three new international studies are helping to refine a treatment for peritoneal mesothelioma that involves rinsing the body cavity with heated chemotherapy drugs. The treatment, called heated intraperitoneal chemotherapy or HIPEC, begins with surgery to remove as much of the mesothelioma tumor as possible from the surface of the peritoneal membrane. Chemotherapy drugs are then heated and rinsed through the area while the patient is still in surgery. The goal is to destroy any residual cancer cells and keep mesothelioma from growing back. Although the treatment is still relatively new, it is quickly becoming the standard of care for peritoneal mesothelioma. Now, researchers around the world are working on ways to make HIPEC even more effective. In one new … Continue reading Refining CRS-HIPEC for Peritoneal Mesothelioma »

Could Your Hairdryer Cause Mesothelioma?

A recent issue of the International Journal of Occupational and Environmental Health contains some sobering news for hairstylists. A frightening new report highlights the potential link between the frequent use of hairdryers and a higher risk of deadly malignant mesothelioma. Hairdressers are not typically counted among the occupations at elevated risk for mesothelioma. Construction workers, electricians, plumbers, and others who work with asbestos-containing insulation have the highest incidence of mesothelioma, which is caused by inhaling the tiny fibers. But the same qualities that make asbestos such a good insulator in construction products, also make it ideal as an insulator and heat shield inside hairdryers. Hundreds of models from almost every major manufacturer were once made with asbestos. The asbestos heat shields were … Continue reading Could Your Hairdryer Cause Mesothelioma? »

New Treatments Have Improved Outcomes for Peritoneal Mesothelioma

The newest studies on peritoneal mesothelioma indicate that the outlook for people with this rare asbestos-linked cancer are better than ever. A recent article in the World Journal of Gastroenterology detailed the progress that has been made – and continues to be made – in the treatment of peritoneal mesothelioma in the last decade. Peritoneal mesothelioma is a type of mesothelioma that occurs on the peritoneum, the lining around the abdominal organs. It accounts for less than a third of mesothelioma cases. In the new article, surgeons with Virginia Commonwealth University’s School of Medicine and the Massey Cancer Center in Richmond report that the increasing use of cytoreductive surgery combined with a rinse of heated chemotherapy drugs has significantly improved … Continue reading New Treatments Have Improved Outcomes for Peritoneal Mesothelioma »

Long Term Survival Possible with CRS/HIPEC for Mesothelioma

There’s hopeful news for peritoneal mesothelioma patients facing the prospect of surgery. A new study on the benefits of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) finds that both the process and outcomes have improved over time. Cytoreductive surgery refers to any surgery aimed at removing as much cancerous tissue as possible. With peritoneal cancers such as mesothelioma, the surgeons may follow the procedure with a wash of heated chemotherapy drugs into the open body cavity. The goal of HIPEC is to destroy any remaining mesothelioma cells and to help keep new mesothelioma cells from growing. A study of 1,000 cytoreductive surgery/HIPEC patients, 72 of whom had mesothelioma, found that complications have decreased and survival has increased for all of … Continue reading Long Term Survival Possible with CRS/HIPEC for Mesothelioma »

Mesothelioma Treatment May Get a Boost from Pineapple Enzyme

There’s new evidence that an enzyme found in pineapples may make peritoneal mesothelioma cells more susceptible to the toxic effects of chemotherapy. Mesothelioma is an aggressive malignancy with a poor prognosis, largely due to the fact that standard treatments, including chemotherapy, are not usually very effective. The pineapple-derived enzyme bromelain has been shown in previous studies to have a negative impact on breast and pancreatic cancer cells. Now, Australian researchers have found that it may also be toxic to peritoneal mesothelioma cells, especially when used along with the drug cisplatin. Bromelain works against cancer by breaking down a protein called MUC-1. Found in several different mesothelioma cell lines, MUC-1 helps cancer cells invade, spread and withstand the toxic effects of … Continue reading Mesothelioma Treatment May Get a Boost from Pineapple Enzyme »

Both Pleural and Peritoneal Mesothelioma Connected to Asbestos

Italy has one of the highest rates of mesothelioma in the world and according to two new studies, mesothelioma rates are a “suitable indicator” of asbestos exposure for both peritoneal and pleural mesothelioma. Asbestos has long been known to be the cause of mesothelioma.  Italian researchers have highlighted this association by analyzing Italian mesothelioma data from 1995-2002.  They discovered that the annual mortality rate was 1.9 per 100,000. Significant mesothelioma clusters were found in the industries often associated with asbestos exposure, including: asbestos-cement industries, shipyards, oil refineries and petrochemical industries.  The authors concluded that their study “confirms malignant pleural neoplasms mortality as a suitable indicator of asbestos exposure at geographic level.” In a related study, Italian researchers examined the relationship between … Continue reading Both Pleural and Peritoneal Mesothelioma Connected to Asbestos »