New Drug Combination May Extend Mesothelioma Survival
A drug derived from the eggs of leopard frogs may offer new hope for people with intractable malignant mesothelioma – especially if the drug is administered in combination with a malaria drug called dihydroartemisinin (DHA). A newly-published Chinese report suggests that the combination has anti-tumor effects on non-small cell lung cancer and malignant mesothelioma not seen with conventional cancer drugs. A Winning Drug Combination? Onconase (also known as Ranpirnase) is a cytotoxic enzyme found in the stem cells of leopard frog eggs and early embryos. It has been used in chemotherapy to help treat malignant mesothelioma, a cancer that is highly resistant to standard cancer drugs. Studies have shown that Onconase can help shrink mesothelioma tumors by attaching itself to…