Tag Archives: second-line treatment

Maintenance Therapy with Gemcitabine Extends Mesothelioma Survival in Dutch Study

maintenance therapy

Dutch researchers say administering maintenance therapy with gemcitabine after chemotherapy may help mesothelioma patients live longer than supportive care alone.  Gemcitabine is an antimetabolite sold under the brand name Gemzar. Oncologists use it to treat several other types of cancer. When cancer cells absorb gemcitabine, they can no longer divide into new cancer cells.  Most mesothelioma patients have chemotherapy as their first-line treatment. If they are healthy enough, they may also have mesothelioma surgery. A maintenance therapy is a treatment that follows the main treatment. It is an effort to maintain the effects of the treatment.  The new Dutch study shows gemcitabine may be a safe and effective choice for maintenance therapy. What Does Maintenance Therapy Mean? Right now, there … Continue reading Maintenance Therapy with Gemcitabine Extends Mesothelioma Survival in Dutch Study »

Second-Line Mesothelioma Treatment with Ramucirumab

second-line mesothelioma treatment

A combination of ramucirumab (CYRAMZA) and gemcitabine creates a promising second-line mesothelioma treatment. New research shows the combination nearly doubled survival in a group of patients whose tumors kept growing with standard therapy.  Italian researchers shared their findings at the virtual annual meeting of ASCO. ASCO is one of the largest gatherings of cancer doctors in the US. First-Line Mesothelioma Treatment Failure For most mesothelioma patients, chemotherapy with Alimta is the first-line treatment. This does keep the cancer in check for some patients. But after a while, mesothelioma tumors almost always come back. Chemotherapy only extends survival by about four months.  Doctors have tested many different approaches to second-line mesothelioma treatment.  Some of the therapies tested are: Additional rounds of … Continue reading Second-Line Mesothelioma Treatment with Ramucirumab »

Second-Line Treatment for Mesothelioma with Lurbinectedin

second-line treatment for mesothelioma

Swiss researchers may have finally found an effective second-line treatment for mesothelioma.  Scientists with the Swiss Group for Clinical Cancer Research presented their findings at the recent European Society for Medical Oncology conference in Barcelona.  Mesothelioma patients who fail after first-line therapy have few options. The new study focused on lurbinectedin, a drug that impacts cancer cells at the DNA level. Early studies suggest lurbinectedin might make a good second-line treatment for small cell lung cancer.  According to the Swiss team, more than half of patients in their study responded to lurbinectedin as a second-line treatment for mesothelioma.  In Search of a Second-Line Mesothelioma Treatment Malignant mesothelioma is notoriously difficult to diagnose and even harder to treat. It is usually … Continue reading Second-Line Treatment for Mesothelioma with Lurbinectedin »