Tag Archives: mesothelioma research

Belgian Mesothelioma Survival Study

mesothelioma survival study

A new Belgian mesothelioma survival study contains important insights for patients and doctors. Cancer center researchers did the study with data from the Belgian Cancer Registry. It includes more than 1400 patients. They received mesothelioma diagnosis between 2004 and 2012. The analysis is similar to past mesothelioma research. It shows the longest-surviving patients are the ones who have chemotherapy. Surgery patients also live longer. The third longer-living group are patients treated at experienced cancer centers. Mesothelioma Survival and Treatment The mesothelioma survival study asks what kinds of patients live longest and why. Researchers had to first see what treatments most patients receive. They found that most mesothelioma patients have chemotherapy. Chemotherapy usually includes pemetrexed (Alimta) and cisplatin. This is the … Continue reading Belgian Mesothelioma Survival Study »

Updated Guidelines Aim to Advance Mesothelioma Research

The criteria for measuring treatment response in malignant pleural mesothelioma is being revised—again. Researchers are hopeful that the new criteria will improve the quality and value of mesothelioma clinical trials and move researchers closer to a cure. Researchers at the University of Chicago and the National Centre for Asbestos Related Diseases in Australia are proposing new modifications to the “modified RECIST” criteria by which researchers currently assess the response of mesothelioma tumors. In order for mesothelioma clinical trials to be truly valuable—and have any chance of leading to a cure—researchers must be “on the same page” in how they assess the size of mesothelioma tumors and their response to treatment. Because malignant mesothelioma is so rare, there are fewer studies … Continue reading Updated Guidelines Aim to Advance Mesothelioma Research »

Immunotherapy “Cocktail” Destroys Mesothelioma Tumors in Lab Mice

There is some exciting news on the mesothelioma research front from The University of Western Australia. Researchers there have successfully cured mesothelioma in mice using immunotherapy. Australia’s long history with asbestos has given it the distinction of having one of the highest rates of mesothelioma in the world. It is also the location of some of the most cutting-edge mesothelioma research. The latest study, conducted by the School of Pathology and Laboratory Medicine at UWA and published in the Journal of Interferon and Cytokine Research, suggests that a “cocktail” of drugs to simulate the immune system can eradicate mesothelioma tumors.  The researchers used a timed triple immunotherapy (TTI) protocol of three antibodies designed to “turn off” the production of specific proteins associated … Continue reading Immunotherapy “Cocktail” Destroys Mesothelioma Tumors in Lab Mice »

Using Cancer Statistics to Prioritize Mesothelioma Research

New cancer statistics from Quebec, Canada suggest that mesothelioma should be a research priority for scientists looking into work-related illnesses. Quebec was once Canada’s heaviest producer and exporter of asbestos, the number one worldwide cause of deadly malignant pleural mesothelioma. In recent years, the number of asbestos-related diseases such as mesothelioma, asbestosis, lung cancer and pleural plaques have been steadily rising and some Canadian health experts warn that the country is poised for a health crisis because of its close ties with the asbestos industry. But exact numbers of work-related cancer cases are not easy to find. Researchers from the Canada School of Public Health at the University of Montreal attempted to estimate the number of work-related cancer cases and … Continue reading Using Cancer Statistics to Prioritize Mesothelioma Research »

Predicting Mesothelioma Outcomes with Blood Tests

Test Tubes

Two separate teams of Japanese researchers are delving into the possibilities of blood serum indicators that could help predict outcomes in patients with malignant pleural mesothelioma. Mesothelioma is a rare but aggressive cancer caused by exposure to asbestos. Pleural mesothelioma, a cancer that starts on the lining around the lungs, is the most common form of the disease. It occurs most often in people who have inadvertently inhaled asbestos dust. Mesothelioma is highly resistant to conventional treatments. It is also difficult to predict which patients are likely to do well with standard therapies and which are not, which is referred to as prognosis. But researchers worldwide are continually searching for new ways to diagnose and predict the prognosis of patients with … Continue reading Predicting Mesothelioma Outcomes with Blood Tests »

Mesothelioma Surgery Under Fire Again

The group that stirred worldwide debate among medical specialists last year with their stance against a radical mesothelioma surgery is taking up the controversial topic once again. Led by prominent Los Angeles-based mesothelioma doctor Robert Cameron, MD, Director of the UCLA Mesothelioma Comprehensive Research Program, the group includes experts from San Francisco, New York and as far away as South Africa. In addition to an interest in the rare asbestos-linked cancer mesothelioma, these experts share a common dislike for extrapleural pneumonectomy (EPP), a major surgical procedure that is still considered by some to be the ‘gold standard’ surgical treatment for this disease. Introduced in the 1940’s and modified over the years, EPP is a mesothelioma surgery that involves removal of … Continue reading Mesothelioma Surgery Under Fire Again »

Major Boost for Mesothelioma Research

Mesothelioma research was given a valuable shot in the arm recently when one of the world’s top research centers for the disease received its second largest donation ever. The $3.58 million anonymous gift to the University of Hawaii Cancer Center will fund studies on ways to treat and prevent mesothelioma, a rare but virulent cancer that is caused by exposure to asbestos. Dr. Michael Carbone, director of the UH Cancer Center, is one of the nation’s top experts on mesothelioma. Dr. Carbone and his team dramatically advanced the understanding of mesothelioma in 2010 with their published study on the mechanism by which asbestos affects the body at the cellular level to trigger the disease. Their research showed that inflammation, caused … Continue reading Major Boost for Mesothelioma Research »

Study Advises Caution For Mesothelioma Blood Test

Australian researchers are warning that a blood test used to help diagnose mesothelioma could indicate the presence of another disease instead. Mesothelin is a protein that occurs naturally in cells of the mesothelium, the membrane that surrounds and protects internal organs. The recent finding that blood levels of mesothelin are elevated in mesothelioma patients was a breakthrough for the asbestos-linked cancer that can be difficult to diagnose.  More than half of the mesothelioma patients tested had significantly elevated serum mesothelin at diagnosis, prompting doctors to begin using serum mesothelin as a diagnostic tool. But now a new study suggests that serum mesothelin can also be significantly elevated in people with kidney disease and recommends that doctors take that into consideration when looking … Continue reading Study Advises Caution For Mesothelioma Blood Test »

Predicting Mesothelioma Outcomes Based on New Research

Certain clinical and laboratory results can help doctors predict which patients are likely to do better than others in their battle against malignant pleural mesothelioma.  That’s the conclusion of a group of researches in Turkey who evaluated the medical charts of 363 malignant pleural mesothelioma patients who had been diagnosed over a span of 20 years. Malignant pleural mesothelioma is a rare but aggressive cancer of the lining around the lungs, also called the pleura.  While it is always a serious health challenge, understanding an individual patient’s prognosis can help doctors with treatment and palliative planning – without having to perform invasive procedures. For this latest study, to be published in the peer-reviewed journal Respiration, The Turkish researchers looked at … Continue reading Predicting Mesothelioma Outcomes Based on New Research »